$77.00
Tretinoin TAAN Cream is a pharmacist-compounded, prescription-only facial treatment that combines tretinoin, azelaic acid, and niacinamide in one topical cream.
The three active ingredients work through complementary pathways to address acne, clogged pores, uneven pigmentation, post-inflammatory marks, rough texture, visible redness, and early signs of photoageing. Tretinoin promotes skin-cell turnover and collagen remodelling, azelaic acid supports clearer and more even-looking skin, and niacinamide helps strengthen the moisture barrier and reduce visible inflammation.
The cream is supplied in an airtight 30 g pump and is available in three graduated tretinoin strengths, allowing the prescribing clinician to select a formula based on the patient’s skin tolerance and treatment needs. It is intended for nightly use on clean, intact facial skin.
Tretinoin binds to retinoic acid receptors in skin cells, influencing genes involved in keratinocyte differentiation, cell turnover, and collagen production.
Azelaic acid helps reduce acne-related microbial activity, supports normal follicular shedding, limits oxidative stress, and interferes with tyrosinase activity involved in pigmentation.
Niacinamide supports cellular energy and barrier repair, reduces inflammatory signalling, and helps limit the transfer of melanin into epidermal cells.
Together, these actions are intended to improve acne, post-inflammatory marks, tone, texture, and early photoageing while helping reduce the irritation burden associated with tretinoin treatment alone.
Use only as directed by the prescribing healthcare professional.
Applying tretinoin to damp skin may increase irritation.
Tretinoin is the active form of vitamin A. It accelerates epidermal cell turnover, helps prevent the formation of comedonal plugs, and supports collagen remodelling within the skin.
With consistent prescribed use, it may help improve:
Tretinoin can also initially cause dryness, peeling, redness, or an acne-like adjustment period.
Azelaic acid is a dicarboxylic acid with comedolytic, antimicrobial, anti-inflammatory, and pigment-supporting properties.
It helps:
Niacinamide is a form of vitamin B3 that supports the skin barrier and helps reduce inflammation.
It may help:
Niacinamide is included partly to help offset some of the dryness and barrier disruption associated with tretinoin.
Empower Pharmacy does not publish a dedicated clinical trial for the exact compounded Tretinoin TAAN Cream formula. However, the active ingredients are clinically established for acne, uneven texture, and post-inflammatory pigmentation.
According to Empower Pharmacy, many patients may notice smoother skin texture by approximately week 4, while more significant improvement in acne and dark post-acne marks may occur between weeks 8 and 12. Continued improvements in tone, texture, and visible photoageing may develop for up to six months with consistent prescribed use.
Published evidence also suggests that combining tretinoin with azelaic acid can improve pigmentation more effectively than azelaic acid alone over approximately three months. Individual results vary, and the treatment should be used under professional supervision.
Wash the skin and let it dry.
Use one pea-sized amount at night.
Keep away from eyes and lips.
Follow with moisturiser when needed.
Supports skin-cell turnover, smoother texture, and clearer-looking pores.
Helps improve visible redness, blemishes, and uneven pigmentation.
Supports the moisture barrier and helps calm visible inflammation.
Price range: $75.00 through $170.00
Price range: $69.00 through $144.00
Price range: $140.00 through $365.00
Price range: $69.00 through $144.00
It is a prescription compounded facial cream containing tretinoin, azelaic acid, and niacinamide for acne, pigmentation, texture, and early photoageing concerns.
The appropriate strength depends on skin tolerance, previous retinoid use, and the condition being treated. The prescribing clinician must select the formula.
It is designed for nightly use, but new or sensitive users may begin a few nights per week and gradually increase frequency as tolerated.
Smoother texture may become noticeable in around four weeks. Acne and pigmentation changes often require eight to twelve weeks, while photoageing improvements may continue for several months.
Some users may experience temporary increased breakouts as existing microcomedones move toward the skin surface. It generally settles as the skin adjusts, but persistent worsening should be reviewed professionally.
Yes. A gentle, non-comedogenic moisturiser can help manage dryness, peeling, and tightness.
